API compatibility

Amazon Bedrock supports four families of runtime APIs, each designed for different integration patterns and use cases.

Invoke family: InvokeModel handles synchronous, single-response calls. InvokeModelWithResponseStream returns responses as a real-time stream. InvokeModelWithBidirectionalStream enables full-duplex streaming for interactive applications. AsyncInvoke submits long-running requests asynchronously, storing output to Amazon S3.

Converse family: Converse provides a unified, model-agnostic interface for synchronous multi-turn conversations. ConverseStream delivers the same experience with streaming output.

OpenAI-compatible family: ChatCompletions implements the OpenAI Chat Completions interface, enabling existing OpenAI-based integrations to run on Bedrock with minimal changes. Responses API implements the OpenAI Responses interface, supporting stateful, agentic interactions with built-in tool use and conversation history management.

Messages family: Messages implements the Anthropic Messages interface on the bedrock-mantle endpoint, enabling existing Anthropic SDK-based integrations to run on Bedrock with minimal changes.

We will now look at the list of APIs supported by each model.

AI21

Amazon

Anthropic

Cohere

DeepSeek

Google

Meta

MiniMax

Mistral

Moonshot

NVIDIA

OpenAI

Qwen

Stability

TwelveLabs

Writer

xAI

Z.AI

Models supporting StartAsyncInvoke

StartAsyncInvoke is an Amazon Bedrock Runtime API that allows callers to submit a model invocation request and immediately receive back an invocationArn without waiting for the model to finish processing. The job runs in the background, and the output is written to a caller-specified S3 bucket once complete. Callers can then poll job status using the companion GetAsyncInvoke and ListAsyncInvokes APIs. The pattern is purpose-built for workloads involving large or latency-insensitive inputs, particularly video, audio, and bulk embedding generation, where holding an open synchronous connection would be impractical.

In terms of which models support it, the following models support StartAsyncInvoke:

InvokeModelWithBidirectionalStream

InvokeModelWithBidirectionalStream is an Amazon Bedrock Runtime API that establishes a persistent, full-duplex channel between the caller and the model, allowing audio data to flow in both directions simultaneously and continuously. Unlike the standard InvokeModel or even InvokeModelWithResponseStream APIs, which follow a request-then-response pattern, this API keeps the connection open for the duration of a session so that the model can process incoming audio as it arrives and stream generated speech back in near real-time, without waiting for a complete utterance to finish. The interaction is structured around three phases: session initialization (where the client sends configuration events to set up the stream), audio streaming (where captured audio is encoded and sent as a continuous event stream), and response streaming (where the model simultaneously returns text transcriptions of user speech and synthesized audio output). InvokeModelWithBidirectionalStream cannot be used with Amazon Bedrock API keys and requires standard AWS credential-based authentication, reflecting its more complex session lifecycle compared to other Bedrock Runtime operations.

The following models support this API: